Opium addiction alters immune responses to stresses such as an injury due to changing the secretion of cytokines. The present study assessed the effect of opium addiction on the cytokines [tumor necrosis factor α (TNFα), interferon-γ (IFN-γ), interleukin-4 (IL-4), and IL-10] before and after laparotomy.
Methods
Male rats were randomly divided into control and opium addicted (n= 20). Then, cytokines were measured before surgery, immediately after surgery (within 30-60 minutes) and 24 hours after surgery.
نام مقاله:
Impact of opium addiction on levels of pro-and anti-inflammatory cytokines after surgery
نویسندگان:
Mohammad Reza Lashkarizadeh, Mohammad Garshasbi, Mohammad Shabani, Shahriar Dabiri, Hadi Hadavi, Hasan Manafi-Anari
نام مجله:
Journal Addiction & Health