According to the results, the adequate architectural design for a medical laboratory includes the following points: observing the separation of physical spaces, proximity of the spaces in the laboratory, the principle of flexibility in designing physical space and the ability to develop and expand the physical space, the space design and requirements to meet the mobility needs of the people with disabilities, desk designing for the disabled and the elderlies, observing the minimum standards of general space and total spaces, and the number of staff considering their safety. Conclusion: The design of medical laboratories, considering the cases mentioned in this report, will lead to the construction of a place that will not only meet the needs of clients but also provide comfort and safety for the staff. Such a laboratory will be more profitable by increasing the productivity, which will ultimately lead to a comprehensive profit. The errors and mistakes in the design and execution of any of these cases can cause minor and major damages.